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Formed in 2008, ISAM is an Alternative Investment Adviser whose management team has amassed over 150 years of combined experience within the quantitative alternative investment space. The management team has deep experience in institutional Alternative Asset Management, particularly Trend Following strategies.

The flagship program, ISAM Systematic Trend, is a pure Trend Following strategy and traces its roots back to 1981. The underlying system was originally developed and maintained by Mint (Man International) and became the first CTA to reach $1bn under management during its 15-year joint venture with Man Group. In May 2010, with Stanley Fink as CEO, ISAM acquired the successful system with its 30-year track record.

Roy Sher and Alex Lowe became managing Partners in 2011, and began developing the business by carefully expanding the various teams. A new London-based research team was formed, whilst the operations function migrated to London. The process culminated with Alex Greyserman being appointed as Chief Scientist for ISAM, overseeing the US office, and Darren Upton becoming CIO of ISAM Systematic Trend in 2012.

Since 2012, the firm has grown steadily with respect to both AUM and staff. The research and development team effort has produced a number of white papers for external use, as well as its proprietary internal work. In 2015, ISAM's Chief Scientist published the book “Trend Following with Managed Futures: The Search for Crisis Alpha”.

In January 2015, ISAM set up IS Prime, a prime-of-prime business offering margin and liquidity in foreign exchange to the online brokerage community. The asset management business is not a client of IS Prime, nor is IS Prime a client of the asset management business. No trades between the two business lines offset or touch each other.

Today, ISAM has 76 employees worldwide with offices in London, Boca Raton, Dubai, Melbourne, Grand Cayman and Grand Rapids.